The intracellular delivery of nucleic acids offers unprecedented promise for revolutionizing biomedical research and novel drug development; however, the nucleic acid delivery vehicle plays a central yet elusive role in dictating the efficacy, safety, mechanisms and kinetics of gene regulation in a spatial and temporal manner.
Dr. Theresa Reineke, the Lloyd H. Reyerson Professor of Chemistry at the University of Minnesota, will discuss several novel carbohydrate-containing polymers developed by her research group. These polymers have shown outstanding affinity to encapsulate polynucleotides into nanoparticles termed polyplexes and facilitate highly efficient intracellular delivery without toxicity.
Chemistry Seminars are held at 3 p.m. each Friday in Room 251, Owens Science Hall. The UST Department of Chemistry welcomes and encourages all to attend.